Top Human Experimentation Anime Recommendations

ONE PIECE

Also known as ONE PIECE.

Studio: Toei Animation
Status: Releasing
Genres: Action , Adventure , Comedy , Drama , Fantasy

Gold Roger was known as the Pirate King, the strongest and most infamous being to have sailed the Grand Line. The capture and death of Roger by the World Government brought a change throughout the world. His last words before his death revealed the location of the greatest treasure in the world, One Piece. It was this revelation that brought about the Grand Age of Pirates, men who dreamed of finding One Piece (which promises an unlimited amount of riches and fame), and quite possibly the most coveted of titles for the person who found it, the title of the Pirate King.

Enter Monkey D. Luffy, a 17-year-old boy that defies your standard definition of a pirate. Rather than the popular persona of a wicked, hardened, toothless pirate who ransacks villages for fun, Luffy’s reason for being a pirate is one of pure wonder; the thought of an exciting adventure and meeting new and intriguing people, along with finding One Piece, are his reasons of becoming a pirate. Following in the footsteps of his childhood hero, Luffy and his crew travel across the Grand Line, experiencing crazy adventures, unveiling dark mysteries and battling strong enemies, all in order to reach One Piece.

*This includes the following special episodes:
- Chopperman to the Rescue! Protect the TV Station by the Shore! (Episode 336)
- The Strongest Tag-Team! Luffy and Toriko's Hard Struggle! (Episode 492)
- Team Formation! Save Chopper (Episode 542)
- History's Strongest Collaboration vs. Glutton of the Sea (Episode 590)
- 20th Anniversary! Special Romance Dawn (Episode 907)

Tags: Pirates , Travel , Shounen , Ensemble Cast , Super Power , Found Family , Male Protagonist , Ships , Conspiracy , Tragedy , Slapstick , Prophecy , Politics , Time Skip , Royal Affairs , War , Slavery , Dystopian , Fugitive , Crime , Gods , Lost Civilization , Swordplay , Henshin , Cyborg , Monster Boy , Primarily Adult Cast , Shapeshifting , Anti-Hero , Food , Philosophy , Animals , Robots , Anthropomorphism , Skeleton , Anachronism , Guns , Desert , Medicine , Samurai , Prison , Post-Apocalyptic , Espionage , Indigenous Cultures , Drugs , Artificial Intelligence , Kuudere , Monster Girl , Fairy , Revenge , Aromantic , Marriage , Assassins , Dragons , Battle Royale , Demons , Adoption , Mermaid , Ninja , Time Manipulation , Angels , Kabuki , Kaiju , Clone , Zombie , Arranged Marriage , Gender Bending , Blackmail , Trains , Unrequited Love , Human Experimentation , Dinosaurs , Interspecies , Fake Relationship , Brainwashing , Transgender

Tokyo Ghoul

Also known as Tokyo Ghoul.

Studio: Studio Pierrot
Status: Finished
Genres: Action , Drama , Horror , Mystery , Psychological , Supernatural

The suspense horror/dark fantasy story is set in Tokyo, which is haunted by mysterious "ghouls" who are devouring humans. People are gripped by the fear of these ghouls whose identities are masked in mystery. An ordinary college student named Kaneki encounters Rize, a girl who is an avid reader like him, at the café he frequents. Little does he realize that his fate will change overnight.



Tags: Gore , Urban Fantasy , Tragedy , Survival , Body Horror , Human Experimentation , Male Protagonist , Torture , Henshin , Seinen , Anti-Hero , Coming of Age , Cannibalism , Urban , Police , Detective , Crime , Primarily Adult Cast , Mythology , Military , Terrorism , College , Heterosexual , Femboy , Monster Boy

Hagane no Renkinjutsushi: FULLMETAL ALCHEMIST

Also known as Fullmetal Alchemist: Brotherhood.

Studio: bones
Status: Finished
Genres: Action , Adventure , Drama , Fantasy

"In order for something to be obtained, something of equal value must be lost."

Alchemy is bound by this Law of Equivalent Exchange—something the young brothers Edward and Alphonse Elric only realize after attempting human transmutation: the one forbidden act of alchemy. They pay a terrible price for their transgression—Edward loses his left leg, Alphonse his physical body. It is only by the desperate sacrifice of Edward's right arm that he is able to affix Alphonse's soul to a suit of armor. Devastated and alone, it is the hope that they would both eventually return to their original bodies that gives Edward the inspiration to obtain metal limbs called "automail" and become a state alchemist, the Fullmetal Alchemist.

Three years of searching later, the brothers seek the Philosopher's Stone, a mythical relic that allows an alchemist to overcome the Law of Equivalent Exchange. Even with military allies Colonel Roy Mustang, Lieutenant Riza Hawkeye, and Lieutenant Colonel Maes Hughes on their side, the brothers find themselves caught up in a nationwide conspiracy that leads them not only to the true nature of the elusive Philosopher's Stone, but their country's murky history as well. In between finding a serial killer and racing against time, Edward and Alphonse must ask themselves if what they are doing will make them human again... or take away their humanity.



Tags: Alchemy , Conspiracy , Military , War , Tragedy , Shounen , Politics , Male Protagonist , Philosophy , Ensemble Cast , Coming of Age , Fugitive , Super Power , Foreign , Gods , Steampunk , Disability , Cyborg , Revenge , Necromancy , Travel , Lost Civilization , Anachronism , Chimera , Dissociative Identities , Primarily Male Cast , Religion , Gore , Slapstick , Orphan , Human Experimentation , Body Horror , Urban Fantasy , Guns , Kuudere , Shapeshifting , Demons , Chibi , Trains , Swordplay , Adoption , Cannibalism , Heterosexual , Desert , Tanned Skin , Tsundere , Zombie , Snowscape , Crossdressing , Cultivation

Steins;Gate

Also known as Steins;Gate.

Studio: WHITE FOX
Status: Finished
Genres: Drama , Psychological , Sci-Fi , Thriller

Self-proclaimed mad scientist Okabe Rintarou lives in a small room in Akihabara, where he invents "future gadgets" with fellow lab members Shiina Mayuri, his air-headed childhood friend, and Hashida Itaru, an otaku hacker. The three pass the time by tinkering with their latest creation, a "Phone Microwave" that can be controlled through text messages.

The lab members soon face a string of mysterious incidents that lead to a game-changing discovery: the Phone Microwave can send emails to the past and thus alter history. Adapted from the critically acclaimed visual novel by 5pb. and Nitroplus, Steins;Gate takes Okabe to the depths of scientific theory and human despair as he faces the dire consequences of changing the past.

Tags: Time Manipulation , Alternate Universe , Time Loop , Conspiracy , Tragedy , Memory Manipulation , Male Protagonist , Urban , Dystopian , Primarily Adult Cast , Chuunibyou , Dissociative Identities , Cosmic Horror , Tsundere , Otaku Culture , Heterosexual , Femboy , Ensemble Cast , Kuudere , Suicide , Criminal Organization , Amnesia , Transgender , War , Clone , Cosplay , Espionage , Human Experimentation , Post-Apocalyptic , Gender Bending , Seinen , Maids , Trains , Shrine Maiden , LGBTQ+ Themes , Detective , Gore , Tomboy

Darling in the Franxx

Also known as DARLING in the FRANXX.

Studio: TRIGGER , CloverWorks
Status: Finished
Genres: Action , Drama , Mecha , Psychological , Romance , Sci-Fi

The distant future: Humanity established the mobile fort city, Plantation, upon the ruined wasteland. Within the city were pilot quarters, Mistilteinn, otherwise known as the “Birdcage.” That is where the children live... Their only mission in life was the fight. Their enemies are the mysterious giant organisms known as Kyoryu. The children operate robots known as FRANXX in order to face these still unseen enemies. Among them was a boy who was once called a child prodigy: Code number 016, Hiro. One day, a mysterious girl called Zero Two appears in front of Hiro. “I’ve found you, my Darling.”



Tags: Cohabitation , Psychosexual , Super Robot , Orphan , Post-Apocalyptic , Primarily Teen Cast , Dystopian , Coming of Age , Tragedy , Robots , Heterosexual , Conspiracy , Kaiju , Monster Girl , Lost Civilization , Found Family , Memory Manipulation , Aliens , Male Protagonist , Travel , Environmental , Love Triangle , Military , Politics , Unrequited Love , Survival , Tsundere , Demons , LGBTQ+ Themes , Space , Body Horror , Femdom , Pregnancy , Female Protagonist , Yandere , Gore , Time Skip , Clone , Brainwashing , Interspecies , Human Experimentation

Youkoso Jitsuryoku Shijou Shugi no Kyoushitsu e

Also known as Classroom of the Elite.

Studio: Lerche
Status: Finished
Genres: Drama , Psychological

Koudo Ikusei Senior High School is a leading school with state-of-the-art facilities. The students there have the freedom to wear any hairstyle and bring any personal effects they desire. Koudo Ikusei is like a utopia, but the truth is that only the most superior students receive favorable treatment.

Kiyotaka Ayanokouji is a student of D-class, which is where the school dumps its "inferior" students in order to ridicule them. For a certain reason, Kiyotaka was careless on his entrance examination, and was put in D-class. After meeting Suzune Horikita and Kikyou Kushida, two other students in his class, Kiyotaka's situation begins to change.



Tags: School , Primarily Teen Cast , Male Protagonist , Anti-Hero , Ensemble Cast , Survival , Blackmail , Human Experimentation , Female Harem , Kuudere , Battle Royale , Boarding School , Coming of Age , Coastal , Nudity , Aromantic , Tsundere , Philosophy , Teacher , School Club , Wilderness , Camping , Yuri

Charlotte

Studio: P.A.WORKS
Status: Finished
Genres: Comedy , Drama , Romance , Sci-Fi , Supernatural

Very few adolescent boys and girls develop special abilities. Yuu Otosaka is one such man who uses his ability, unbeknownst to others, in order to lead a satisfying school life. Then one day, a girl named Nao Tomori suddenly appears before him. Their encounter reveals the destiny for wielders of special abilities. This is a story of those gifted youth and how they spend their adolescence.



Tags: Super Power , Time Manipulation , Tragedy , Urban Fantasy , Primarily Teen Cast , Urban , School Club , Male Protagonist , School , Body Swapping , Amnesia , Tsundere , Dissociative Identities , Female Protagonist , Memory Manipulation , Survival , Human Experimentation , Anti-Hero , Heterosexual , Slapstick , Primarily Female Cast , Torture , Delinquents , Tomboy , Mahjong , Yandere , Band , Bullying , CGI , Baseball

Made in Abyss

Also known as Made in Abyss.

Studio: Kinema Citrus
Status: Finished
Genres: Adventure , Drama , Fantasy , Horror , Mystery , Sci-Fi

The "Abyss" is the last unexplored place in the world. Strange and wonderful creatures roam within, and it is full of precious relics that present humans can't recreate. Those that dare to explore the depths are known as "Cave Raiders." An orphan girl named Riko lives on the rim. Her dream is to become a Cave Raider like her mother and solve the mysteries of the cave system. One day, Riko starts exploring the caves and discovers a robot who resembles a human boy.



Note: The last episode aired with a runtime of ~48 minutes as opposed to the standard 24 minute long episode.

Tags: Survival , Outdoor Activities , Primarily Child Cast , Environmental , Travel , Cosmic Horror , Body Horror , Curses , Tragedy , Chibi , Philosophy , Lost Civilization , Dungeon , Seinen , Female Protagonist , Gore , Orphan , Amnesia , Wilderness , Eco-Horror , Anthropomorphism , Robots , Male Protagonist , Steampunk , Nudity , Human Experimentation , Food , Amputation , School , Dissociative Identities , Crossdressing , Religion , Maids , Femboy , Rehabilitation , Time Manipulation

Zankyou no Terror

Also known as Terror in Resonance.

Studio: MAPPA
Status: Finished
Genres: Drama , Mystery , Psychological , Thriller

Painted in red, the word "VON" is all that is left behind after a terrorist attack on a nuclear facility in Japan. The government is shattered by their inability to act, and the police are left frantically searching for ways to crack down the perpetrators. The public are clueless—until, six months later, a strange video makes its way onto the internet. In it, two teenage boys who identify themselves only as "Sphinx" directly challenge the police, threatening to cause destruction and mayhem across Tokyo. Unable to stop the mass panic quickly spreading through the city and desperate for any leads in their investigation, the police struggle to act effectively against these terrorists, with Detective Kenjirou Shibazaki caught in the middle of it all.

Zankyou no Terror tells the story of Nine and Twelve, the two boys behind the masked figures of Sphinx. They should not exist, yet they stand strong in a world of deception and secrets while they make the city fall around them, all in the hopes of burying their own tragic truth.



Tags: Terrorism , Anti-Hero , Detective , Tragedy , Crime , Male Protagonist , Revenge , Orphan , Urban , Police , Politics , Primarily Male Cast , Female Protagonist , Heterosexual , Human Experimentation , Mythology , Philosophy , Motorcycles , Suicide , Software Development , Guns , Time Skip , Shogi , Blackmail

Elfen Lied

Also known as Elfen Lied.

Studio: ARMS
Status: Finished
Genres: Action , Drama , Ecchi , Horror , Psychological , Romance , Supernatural

The Diclonius, a mutated homosapien that is said to be selected by God and will eventually become the destruction of mankind, possess two horns on their heads and have a "sixth sense" which gives them telekinetic abilities. Due to this dangerous power, they have been captured and isolated in laboratories by the government. Lucy, a young and psychotic Diclonius, manages to break free of her confines and brutally murders most of the guards in the laboratory where she is being held, only to be shot in the head as she makes her escape. She survives, falling off a cliff into the ocean and manages to drift along to a beach where two teenagers, Kouta and Yuka, discover her. Having lost her memories, she was named after the only thing that she can now say, "Nyuu," and the two allow her to stay at Kouta's home. However, it appears that the psychotic side of Lucy is not dead just yet...



Tags: Gore , Super Power , Fugitive , Monster Girl , Amnesia , Urban Fantasy , Tragedy , Dissociative Identities , Seinen , Body Horror , Anthropomorphism , Revenge , Incest , Nudity , Female Protagonist , Philosophy , Yandere , Conspiracy , Bullying , Coastal , Love Triangle , Cyborg , Primarily Female Cast , Disability , Heterosexual , Male Protagonist , Tsundere , Interspecies , Kemonomimi , Military , Family Life , Rural , Human Experimentation , Primarily Teen Cast , Slapstick , Female Harem , Cohabitation , Animals

Hagane no Renkinjutsushi

Also known as Fullmetal Alchemist.

Studio: bones
Status: Finished
Genres: Action , Adventure , Drama , Fantasy

The rules of alchemy state that to gain something, one must lose something of equal value. Alchemy is the process of taking apart and reconstructing an object into a different entity, with the rules of alchemy to govern this procedure. However, there exists an object that can bring any alchemist above these rules, the object known as the Philosopher's Stone. The young Edward Elric is a particularly talented alchemist who through an accident years back lost his younger brother Alphonse and one of his legs. Sacrificing one of his arms as well, he used alchemy to bind his brother's soul to a suit of armor. This lead to the beginning of their journey to restore their bodies, in search for the legendary Philosopher's Stone.

Note: Episodes 11, 12 and 37 were adapted from the light novel "Fullmetal Alchemist: The Land of Sand."

Tags: Alchemy , Philosophy , Magic , Tragedy , Male Protagonist , Military , Conspiracy , Coming of Age , Shounen , Travel , War , Alternate Universe , Body Horror , Steampunk , Disability , Chimera , Isekai , Foreign , Cyborg , Slapstick , Chibi , Anti-Hero , Religion , Lost Civilization , Trains , Guns , Human Experimentation

Deadman Wonderland

Also known as Deadman Wonderland.

Studio: Manglobe
Status: Finished
Genres: Action , Drama , Sci-Fi , Supernatural

Ganta is the only survivor after a mysterious man in red slaughters a classroom full of teenagers. He's framed for the carnage, sentenced to die, and locked away in the most twisted prison ever built: Deadman Wonderland. And then it gets worse.

At Deadman Wonderland, convicts are forced into brutal deathmatches for the amusement of the masses, the cheers of the crowd drowning out the screams of the dismembered. Even when Ganta befriends Shiro, an unusual female inmate, his dark fate crushes all hope —until he discovers the strange ability to wield his spilled blood as a weapon. Ganta learns his new skill might be related to the murderous man in red and uncovers disturbing secrets that could expose those who stole his freedom. He's determined to see justice served —but first he'll have to fight for his life in a prison that holds a million ways to die.



Tags: Prison , Tragedy , Survival , Super Power , Gore , Death Game , Anti-Hero , Body Horror , Shounen , Male Protagonist , Dissociative Identities , Orphan , Urban Fantasy , Memory Manipulation , Nudity , Guns , Rehabilitation , Tanned Skin , LGBTQ+ Themes , Human Experimentation

AKIRA

Also known as Akira.

Studio: Tokyo Movie Shinsha
Status: Finished
Genres: Action , Adventure , Horror , Psychological , Sci-Fi , Supernatural

It's the year 2019, thirty-one years have passed since the start of World War III. A top-secret child with amazing powers of the mind breaks free from custody and accidentally gets a motorcycle gang involved in the project. This incident triggers psychic powers within one of the gang members, Tetsuo, and he is taken by the army to be experimented on. His mind has been altered and is now on the path of war, seeking revenge on the society that once called him weak.



Tags: Cyberpunk , Post-Apocalyptic , Dystopian , Super Power , Urban , Male Protagonist , Tragedy , Primarily Male Cast , Delinquents , Prophecy , Seinen , Urban Fantasy , Body Horror , Anti-Hero , Motorcycles , Conspiracy , Gangs , Gore , Military , Philosophy , Crime , Orphan , Guns , Politics , Aliens , Mythology , Human Experimentation , Nudity

Tengoku Daimakyou

Also known as Tengoku Daimakyo.

Studio: Production I.G
Status: Finished
Genres: Adventure , Mystery , Sci-Fi , Thriller

In the year 2024, the world has collapsed. Grotesque monsters lurk amongst the ruins of Japan, while remaining people scrape together what they can to survive. Kiruko, an odd-job girl in Nakano, accepts a mysterious woman's dying wish to take a boy named Maru to a place called Heaven.



Tags: Dystopian , Post-Apocalyptic , Survival , Achronological Order , Seinen , Travel , Tragedy , Body Swapping , Conspiracy , Male Protagonist , Gender Bending , Orphan , Super Power , Gore , Denpa , Unrequited Love , Demons , Body Horror , Artificial Intelligence , Pregnancy , Guns , Coming of Age , Nudity , Suicide , Heterosexual , Female Protagonist , LGBTQ+ Themes , Cyberpunk , Transgender , Kuudere , Human Experimentation

Vanitas no Carte

Also known as The Case Study of Vanitas.

Studio: bones
Status: Finished
Genres: Action , Drama , Fantasy , Mystery , Supernatural

It’s 19th-century Paris, and young vampire Noé hunts for the Book of Vanitas. Attacked by a vampire driven insane, a human intercedes, rescues Noé, and heals the sick creature. Commanding the book and calling himself Vanitas, this doctor tempts Noé with a mad crusade to “cure” the entire vampire race. Allying with one who wields arcane power so easily may be dangerous, but does he have a choice?



Tags: Vampire , Male Protagonist , Conspiracy , Foreign , Steampunk , Tragedy , Heterosexual , Primarily Adult Cast , Anti-Hero , Tsundere , Anachronism , Historical , Gore , Tanned Skin , Chibi , Religion , Shounen , Assassins , Surreal Comedy , Primarily Male Cast , Boys' Love , LGBTQ+ Themes , Henshin , Coming of Age , Drugs , Adoption , Super Power , Human Experimentation

Kiznaiver

Also known as Kiznaiver.

Studio: TRIGGER
Status: Finished
Genres: Drama , Romance , Sci-Fi

The fictional Japanese city named Sugomori City is built on reclaimed land. But as the years go by, the city's population is decreasing. One day, Sonozaki tells her classmate Katsuhira: "You have been selected to be a Kiznaiver." The Kizuna System, which allows Katsuhira to share his wounds, connects him to the classmates whose lives and personalities completely differ from his. The Kizuna System is an incomplete system for the implementation of world peace that connects people through wounds. All those who are connected to this system are called Kiznaivers. When one Kiznaiver is wounded, the system divides and transmits the wound among the other Kiznaivers.



Tags: Ensemble Cast , Primarily Teen Cast , Amnesia , Love Triangle , Unrequited Love , Human Experimentation , Coming of Age , Urban , Rehabilitation , Philosophy , Heterosexual , Kuudere , Male Protagonist , Female Protagonist , Tragedy , School , Tsundere , Seinen , Bullying , LGBTQ+ Themes

Owari no Seraph: Nagoya Kessen-hen

Also known as Seraph of the End: Battle in Nagoya.

Studio: WIT STUDIO
Status: Finished
Genres: Action , Drama , Fantasy , Supernatural

Yuuichirou has reunited with Mikaela at the Shinjuku Battle. But Mikaela was turned into a vampire... To save the "family," and to protect his fellow members, Yuuichirou needed to gain knowledge and power. He searched for ways to bring back vampire to human beings, and at the same time, trained hard working on the Cursed Gear.

Meanwhile, Kureto calls Guren and tells him a shocking truth. That in one month, the main unit of the vampire will start attacking Tokyo. To get a head start against vampires, Kureto orders Guren to go to Nagoya. The noble extermination mission is about to open fire!



Tags: Conspiracy , Lost Civilization , Vampire , Post-Apocalyptic , Demons , Military , War , Male Protagonist , Revenge , Shounen , Urban Fantasy , Human Experimentation , Rotoscoping , Swordplay , Gore , Tragedy , Heterosexual , Cosmic Horror , Angels

Jigokuraku 2nd Season

Also known as Hell’s Paradise Season 2.

Studio: MAPPA
Status: Finished
Genres: Action , Adventure , Mystery , Supernatural

Seeking the key to the elixir of immortality, the group arrives at the fortress of the island's monstrous ruler, the "Tensen." To survive and escape the island, cooperation becomes essential—regardless of whether one is a condemned criminal or an executioner.

Meanwhile, the shogunate orders additional landings on the island of the Immortal Realm, led by Shugen Yamada Asayemon. Among them are the Ishigakure clan, who share a past with Gabimaru.

Desperate to find the elixir and escape the island, Gabimaru and his companions face the Tensen in a battle that escalates into an all-out confrontation between humans and immortals!



Tags: Male Protagonist , Survival , Body Horror , Ninja , Samurai , Swordplay , Ensemble Cast , Cultivation , Tragedy , Gore , Super Power , Heterosexual , Gender Bending , Nudity , Martial Arts , Battle Royale , Religion , Historical , Shounen , Amnesia , Yandere , Human Experimentation , Primarily Adult Cast , Gods

Made in Abyss: Fukaki Tamashii no Reimei

Also known as Made in Abyss: Dawn of the Deep Soul.

Studio: Kinema Citrus
Status: Finished
Genres: Action , Adventure , Drama , Fantasy , Horror , Mystery , Psychological , Sci-Fi

Dawn of the Deep Soul continues the epic adventure of plucky Riko and Reg who are joined by their new friend Nanachi. Together they descend into the Abyss’ treacherous fifth layer, the Sea of Corpses, and encounter the mysterious Bondrewd, a legendary White Whistle whose shadow looms over Nanachi’s troubled past. Bondrewd is ingratiatingly hospitable, but the brave adventurers know things are not always as they seem in the enigmatic Abyss...



Tags: Tragedy , Survival , Body Swapping , Primarily Child Cast , Seinen , Lost Civilization , Body Horror , Gore , Anthropomorphism , Curses , Human Experimentation , Robots , Female Protagonist , Dungeon , Nudity , Monster Girl , Amputation , Dissociative Identities , Male Protagonist , Eco-Horror , Chibi , Anti-Hero , Ensemble Cast , Amnesia , Food , Family Life , Magic

Ajin

Also known as AJIN: Demi-Human.

Studio: POLYGON PICTURES
Status: Finished
Genres: Action , Horror , Mystery , Supernatural

Kei Nagai’s body should have died when a truck slams into his body, but instead, he finds himself resurrected with all of his wounds healed. Now revealed to be an Ajin, one of a mysterious new breed of immortal demi-human, he’s been marked with an international bounty, and in the eyes of the world, Kei is a specimen to be taken by any means possible. Now he’s on the run, and his only hope is to discover the terrifying secrets behind his new abilities before he’s forced to use them in battle!



Tags: Anti-Hero , Super Power , Crime , Fugitive , Police , Urban Fantasy , Full CGI , Terrorism , Seinen , Male Protagonist , Criminal Organization , Human Experimentation , Gore , Primarily Male Cast , Body Horror , Dystopian , Primarily Adult Cast , Cosmic Horror , Torture , Motorcycles , Video Games